Cancer cell (2019) · 피인용 834
Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy.

Cell (2020) · 피인용 559
Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes.

Immunity (2021) · 피인용 297
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions.

Cancer cell (2021) · 피인용 164
Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation.

Cell (2022) · 피인용 164
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors.

Cancer cell (2024) · 피인용 123
Inosine induces stemness features in CAR-T cells and enhances potency.

Immunity (2022) · 피인용 150
Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity.

Cell reports (2019) · 피인용 127
Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal Interface.

Cell reports (2021) · 피인용 94
CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia.

Immunity (2020) · 피인용 978
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.

Cell (2020) · 피인용 468
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.

Immunity (2023) · 피인용 110
Stat5 opposes the transcription factor Tox and rewires exhausted CD8<sup>+</sup> T cells toward durable effector-like states during chronic antigen exposure.

Cancer cell (2022) · 피인용 184
Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer.

Immunity (2022) · 피인용 156
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones.

Cell reports (2021) · 피인용 59
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy.

Cell (2021) · 피인용 366
An NK-like CAR T cell transition in CAR T cell dysfunction.

Cell (2018) · 피인용 280
NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines.

Immunity (2021) · 피인용 204
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

Cell (2021) · 피인용 363
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.

Cell reports. Medicine (2021) · 피인용 86
Single-cell transcriptomic landscape reveals tumor specific innate lymphoid cells associated with colorectal cancer progression.

Oncoimmunology (2022) · 피인용 43
Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer.

Immunity (2022) · 피인용 277
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses.

Cancer cell (2024) · 피인용 74
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.

Cancer cell (2024) · 피인용 73
Comprehensive peripheral blood immunoprofiling reveals five immunotypes with immunotherapy response characteristics in patients with cancer.

Cell (2021) · 피인용 363
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.

Cell reports (2020) · 피인용 133
The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections.

Cancer cell (2022) · 피인용 116
Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.

Cell (2020) · 피인용 1338
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

Immunity (2021) · 피인용 204
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

Cell (2019) · 피인용 160
Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells.

Immunity (2021) · 피인용 71
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells.

Cell reports (2024) · 피인용 45
Landscape of tumoral ecosystem for enhanced anti-PD-1 immunotherapy by gut Akkermansia muciniphila.

Cell reports (2021) · 피인용 42
Dynamic adoption of anergy by antigen-exhausted CD4+ T cells.

Cancer cell (2021) · 피인용 230
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer.

Cell (2024) · 피인용 229
LAG-3 and PD-1 synergize on CD8<sup>+</sup> T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity.

Immunity (2020) · 피인용 203
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment.

Cell reports (2020) · 피인용 57
Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation.

Immunity (2021) · 피인용 56
Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.

eLife (2021) · 피인용 31
ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.

Immunity (2020) · 피인용 203
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment.

Cell (2021) · 피인용 82
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy.

Immunity (2025) · 피인용 16
Recirculating regulatory T cells mediate thymic regeneration through amphiregulin following damage.

Immunity (2019) · 피인용 588
Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy.

Immunity (2023) · 피인용 64
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells.

Cell reports (2022) · 피인용 44
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade.

Immunity (2023) · 피인용 74
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.

Journal for immunotherapy of cancer (2024) · 피인용 15
Second-generation checkpoint inhibitors and Treg depletion synergize with a mouse cancer vaccine in accordance with tumor microenvironment characterization.

Cancer research (2024) · 피인용 10
Lipid-Encapsulated mRNAs Encoding Complex Fusion Proteins Potentiate Antitumor Immune Responses.

Immunity (2020) · 피인용 124
Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy.

Cancer cell (2023) · 피인용 88
MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors.

iScience (2023) · 피인용 7
TIGIT contributes to the regulation of 4-1BB and does not define NK cell dysfunction in glioblastoma.

Nature medicine (2021) · 피인용 264
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis.

Cell reports (2022) · 피인용 98
Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy.

Cell metabolism (2023) · 피인용 62
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.

Immunity (2020) · 피인용 124
Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy.

Communications biology (2022) · 피인용 10
Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization.

iScience (2023) · 피인용 9
The transcription factor IRF4 determines the anti-tumor immunity of CD8+ T cells.

Cell (2023) · 피인용 118
Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis.

EMBO molecular medicine (2024) · 피인용 14
LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis.

Cell reports. Medicine (2024) · 피인용 13
An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL.

Cancer cell (2020) · 피인용 371
Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.

Cell reports (2023) · 피인용 24
Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer.

iScience (2024) · 피인용 6
Tumor stage-driven disruption of NK cell maturation in human and murine tumors.

Cell reports (2023) · 피인용 21
A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity.

Cell reports (2023) · 피인용 17
CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions.

Frontiers in immunology (2023) · 피인용 9
The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice.

Cell reports (2019) · 피인용 127
Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal Interface.

Cell reports. Medicine (2023) · 피인용 21
Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes.

STAR protocols (2023) · 피인용 12
Purification of primary human placental leukocytes to study maternal-fetal interactions.

Cell reports (2021) · 피인용 43
Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity.

Cell (2022) · 피인용 36
Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide.

Cell reports. Medicine (2025) · 피인용 6
TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation.