eLife (2019) · 피인용 124
A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS.

Clinical cancer research : an official journal of the American Association for Cancer Research (2021) · 피인용 105
YAP/TAZ Transcriptional Coactivators Create Therapeutic Vulnerability to Verteporfin in EGFR-mutant Glioblastoma.

Developmental cell (2020) · 피인용 88
Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement.

eNeuro (2017) · 피인용 150
Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease.

Cell reports (2022) · 피인용 37
CRAF dimerization with ARAF regulates KRAS-driven tumor growth.

The Journal of biological chemistry (2023) · 피인용 29
Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling.

Cell (2020) · 피인용 240
Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.

Cell stem cell (2021) · 피인용 97
Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids.

Science signaling (2020) · 피인용 83
Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis.

Molecular cell (2019) · 피인용 171
OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.

Immunity (2025) · 피인용 102
Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway.

Cell (2024) · 피인용 74
A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence.

eLife (2019) · 피인용 303
Mitochondrial fusion supports increased oxidative phosphorylation during cell proliferation.

Molecular cell (2022) · 피인용 152
Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells.

Cell chemical biology (2019) · 피인용 43
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.

eLife (2022) · 피인용 26
Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs.

Science advances (2023) · 피인용 8
HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis.

Cancer research (2025) · 피인용 8
CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-Deleted Cancer.

Cell (2021) · 피인용 173
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules.

Cell reports (2019) · 피인용 74
Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.

Molecular cell (2022) · 피인용 15
Regulation of GTPase function by autophosphorylation.

Nature cell biology (2021) · 피인용 135
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.

Oncotarget (2019) · 피인용 16
CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.

Cell (2022) · 피인용 66
XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.

Molecular carcinogenesis (2023) · 피인용 3
Dual role of sprouty2 as an inhibitor of RAS/ERK-driven proliferation and a promoter of cancer invasion in KRAS wild-type colorectal cancer.