Cancer cell (2018) · 피인용 63
A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence.

Nature cell biology (2023) · 피인용 42
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.

Cell reports (2023) · 피인용 37
Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

Cancer cell (2019) · 피인용 362
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.

Molecular cell (2022) · 피인용 61
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape.

Nature communications (2020) · 피인용 57
MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia.

Cell stem cell (2017) · 피인용 161
Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.

Molecular cell (2019) · 피인용 133
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.

Cell reports (2019) · 피인용 28
The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.