Cell (2019) · 피인용 372
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.

eLife (2018) · 피인용 101
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.

Cell reports (2019) · 피인용 75
Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.

Cancer research (2021) · 피인용 77
SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS-STING Activation and Chemotherapeutic Sensitivity in Colon Cancer.

Molecular metabolism (2021) · 피인용 64
LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through the MEK/ERK signaling pathway.

Cell reports (2022) · 피인용 17
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.

Cell (2019) · 피인용 83
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.

Cell reports (2022) · 피인용 43
Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord.

Frontiers in molecular neuroscience (2023) · 피인용 1
Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures.

Cancer cell (2023) · 피인용 84
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.

Developmental cell (2023) · 피인용 20
Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development.

EMBO molecular medicine (2026) · 피인용 0
Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma.

Cell reports. Medicine (2023) · 피인용 45
Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.

Molecular cell (2024) · 피인용 36
mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway.

Clinical and molecular hepatology (2026) · 피인용 1
Targeting ER lipid raft-associated 1 reveals a coordinated cholesterol-dependent vulnerability in hepatocellular carcinoma.

Cell metabolism (2022) · 피인용 31
PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis.

eLife (2021) · 피인용 16
TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states.

International journal of molecular sciences (2022) · 피인용 7
Interleukin-1 Induces the Release of Lubricating Phospholipids from Human Osteoarthritic Fibroblast-like Synoviocytes.