Immunity (2023) · 피인용 432
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.

Cell (2022) · 피인용 330
Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.

Cell (2021) · 피인용 199
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.

Cell metabolism (2021) · 피인용 133
Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.

Immunity (2021) · 피인용 126
Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells.

Immunity (2021) · 피인용 76
Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.

Neural regeneration research (2023) · 피인용 140
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons.

Cell reports (2021) · 피인용 120
Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes.

Neural regeneration research (2023) · 피인용 49
Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage.

Molecular cell (2022) · 피인용 130
Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.

Cancer cell (2023) · 피인용 84
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.

iScience (2023) · 피인용 12
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.

Cell (2022) · 피인용 184
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Cell reports (2021) · 피인용 117
Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases.

Nature communications (2024) · 피인용 26
Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application.

EBioMedicine (2022) · 피인용 78
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.

Cell reports (2024) · 피인용 25
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.

Neural regeneration research (2023) · 피인용 13
TUG-891 inhibits neuronal endoplasmic reticulum stress and pyroptosis activation and protects neurons in a mouse model of intraventricular hemorrhage.

Immunity (2019) · 피인용 232
Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.

Immunity (2020) · 피인용 185
Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.

Cell metabolism (2021) · 피인용 133
Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.

Cell host & microbe (2018) · 피인용 516
Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.

Cell reports (2019) · 피인용 39
Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages.

Frontiers in immunology (2021) · 피인용 32
Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock.

Neural regeneration research (2024) · 피인용 32
Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway.

Neural regeneration research (2023) · 피인용 22
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.

Neural regeneration research (2024) · 피인용 16
Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis.

Neural regeneration research (2024) · 피인용 16
Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis.

Cellular and molecular neurobiology (2023) · 피인용 4
Dopamine Activates the D1R-Zn<sup>2+</sup> Signaling Pathway to Trigger Inflammatory Response in Primary-Cultured Rat Embryonic Cortical Neurons.

eLife (2024) · 피인용 3
G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs.

Cell (2021) · 피인용 123
Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death.

Molecular cell (2023) · 피인용 67
An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.

PeerJ (2024) · 피인용 1
Myoferlin alleviates pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting NLRP3-mediated pyroptosis.

British journal of pharmacology (2022) · 피인용 40
Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.

Neural regeneration research (2024) · 피인용 25
Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation.

Neural regeneration research (2023) · 피인용 14
Bexarotene improves motor function after spinal cord injury in mice.

Cell reports (2024) · 피인용 30
Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease.

Developmental cell (2024) · 피인용 23
D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder.

iScience (2023) · 피인용 6
Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine.

Journal of neuroscience research (2019) · 피인용 138
Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro.

Journal of biochemical and molecular toxicology (2024) · 피인용 7
Nanocurcumin attenuates pyroptosis and inflammation through inhibiting NF-κB/GSDMD signal in high altitude-associated acute liver injury.

Neural regeneration research (2022) · 피인용 28
Lithium promotes recovery after spinal cord injury.

Molecular reproduction and development (2024) · 피인용 1
Pyroptosis is involved in maternal nicotine exposure-induced metabolic associated fatty liver disease progression in offspring mice.