Cell (2018) · 피인용 626
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1.

Molecular cell (2023) · 피인용 107
Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.

Molecular cell (2020) · 피인용 92
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.

Cell metabolism (2019) · 피인용 107
Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.

Neuron (2018) · 피인용 69
Ras and Rap Signal Bidirectional Synaptic Plasticity via Distinct Subcellular Microdomains.

Current biology : CB (2021) · 피인용 47
LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes.

British journal of pharmacology (2020) · 피인용 134
Butyrate protects against high-fat diet-induced atherosclerosis via up-regulating ABCA1 expression in apolipoprotein E-deficiency mice.

EBioMedicine (2022) · 피인용 84
Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBM.

Immunity (2023) · 피인용 67
Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.

Molecular cell (2022) · 피인용 58
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.

Immunity (2024) · 피인용 20
Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation.

Cell metabolism (2025) · 피인용 13
Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV.

Cell (2021) · 피인용 131
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.

Developmental cell (2019) · 피인용 101
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.

eLife (2018) · 피인용 57
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

Cell (2021) · 피인용 131
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.

EMBO reports (2023) · 피인용 15
CCDC50 promotes tumor growth through regulation of lysosome homeostasis.

Cell (2026) · 피인용 14
A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.

Cell reports (2024) · 피인용 23
Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2021) · 피인용 18
Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning.

Frontiers in cardiovascular medicine (2021) · 피인용 11
Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence.

Immunity (2021) · 피인용 189
A subset of Kupffer cells regulates metabolism through the expression of CD36.

Cell (2020) · 피인용 110
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.

Cell metabolism (2017) · 피인용 77
A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function.

Molecular cell (2017) · 피인용 212
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.

eLife (2022) · 피인용 55
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.

Molecular cell (2019) · 피인용 48
mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux.

Cancer cell (2018) · 피인용 194
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Cell reports (2023) · 피인용 28
Heterogeneity and transcriptional drivers of triple-negative breast cancer.

Alzheimer's & dementia : the journal of the Alzheimer's Association (2025) · 피인용 9
Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease.

Journal of neurochemistry (2023) · 피인용 24
The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation.

Cell chemical biology (2021) · 피인용 22
Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis.

Cell reports (2026) · 피인용 1
Activated T cells degrade extracellular proteins to enhance effector functions.

Cell reports (2022) · 피인용 118
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.

Cell reports (2024) · 피인용 8
Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression.

Cell chemical biology (2026) · 피인용 0
A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway.

Cell (2018) · 피인용 985
Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells.

Cell reports (2021) · 피인용 74
BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells.

Cell reports. Medicine (2025) · 피인용 3
iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors.

Cell reports (2019) · 피인용 48
LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion.

Journal of neurochemistry (2018) · 피인용 14
Pallidin is a novel interacting protein for cytohesin-2 and regulates the early endosomal pathway and dendritic formation in neurons.

Cell metabolism (2022) · 피인용 38
Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context.

STAR protocols (2023) · 피인용 1
Protocol for multispectral imaging on cryosections to map myeloid cell heterogeneity in its spatial context.

Immunity (2021) · 피인용 137
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming.

Cell reports (2024) · 피인용 9
ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.

Developmental cell (2019) · 피인용 66
Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment.

Molecular neurodegeneration (2021) · 피인용 52
Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.

Cell reports (2021) · 피인용 19
UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability.

iScience (2023) · 피인용 2
Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses.

The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) · 피인용 85
α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.

Cell reports (2023) · 피인용 40
ARL8B mediates lipid droplet contact and delivery to lysosomes for lipid remobilization.

Immunity (2023) · 피인용 41
Loss of CD4<sup>+</sup> T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

Immunity (2025) · 피인용 6
A CD4<sup>+</sup> T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction.

Cell metabolism (2020) · 피인용 344
A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells.

iScience (2022) · 피인용 17
Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy.

Cell reports (2021) · 피인용 47
AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke.

Journal of neurochemistry (2020) · 피인용 24
Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling.