Cell metabolism (2019) · 피인용 855
Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment.

Cell (2018) · 피인용 626
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1.

Cell (2022) · 피인용 542
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.

Cell (2019) · 피인용 2442
Reassessment of Exosome Composition.

Immunity (2019) · 피인용 642
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.

Cell metabolism (2020) · 피인용 517
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.

Neuron (2017) · 피인용 662
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.

Molecular cell (2019) · 피인용 492
N6-Methyladenosine Modification Controls Circular RNA Immunity.

Cell (2018) · 피인용 409
Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds.

Molecular cell (2022) · 피인용 630
Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells.

eLife (2020) · 피인용 124
CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance.

iScience (2022) · 피인용 115
Identification of lysine-lactylated substrates in gastric cancer cells.

Immunity (2019) · 피인용 811
The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.

Cancer cell (2022) · 피인용 760
CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4.

Cancer cell (2019) · 피인용 410
Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy.

Cell (2023) · 피인용 259
Resurrection of endogenous retroviruses during aging reinforces senescence.

Molecular cell (2020) · 피인용 199
Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling.

eLife (2021) · 피인용 156
Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy.

Cell reports (2019) · 피인용 215
Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue.

British journal of pharmacology (2020) · 피인용 134
Butyrate protects against high-fat diet-induced atherosclerosis via up-regulating ABCA1 expression in apolipoprotein E-deficiency mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) · 피인용 90
Adult Hippocampal Neurogenesis along the Dorsoventral Axis Contributes Differentially to Environmental Enrichment Combined with Voluntary Exercise in Alleviating Chronic Inflammatory Pain in Mice.

Cell reports (2019) · 피인용 359
Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK.

Cell (2023) · 피인용 114
Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.

Developmental cell (2021) · 피인용 56
Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration.

Cell reports (2020) · 피인용 311
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2021) · 피인용 89
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.

Cell reports (2019) · 피인용 62
Age- and α-Synuclein-Dependent Degeneration of Dopamine and Noradrenaline Neurons in the Annual Killifish Nothobranchius furzeri.

Molecular cell (2022) · 피인용 83
Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.

Developmental cell (2021) · 피인용 69
Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C.

Cell reports (2020) · 피인용 34
A Requirement for Argonaute 4 in Mammalian Antiviral Defense.

Immunity (2019) · 피인용 348
Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.

Molecular cell (2020) · 피인용 147
Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1.

Cell reports (2020) · 피인용 121
Platelets Fuel the Inflammasome Activation of Innate Immune Cells.

Molecular cell (2021) · 피인용 30
PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.

Cell reports (2023) · 피인용 25
METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis.

Cell reports (2024) · 피인용 13
Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis.

Cell host & microbe (2023) · 피인용 84
Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis.

Cell death & disease (2020) · 피인용 45
Necroptosis in head and neck squamous cell carcinoma: characterization of clinicopathological relevance and in vitro cell model.

Cell reports (2019) · 피인용 35
Metabolic Rewiring in Response to Biguanides Is Mediated by mROS/HIF-1a in Malignant Lymphocytes.

Current biology : CB (2020) · 피인용 65
Arp2/3 and Mena/VASP Require Profilin 1 for Actin Network Assembly at the Leading Edge.

Cancer cell (2023) · 피인용 58
Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.

Cell reports (2020) · 피인용 33
Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling.

Cell reports (2021) · 피인용 53
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability.

Cell reports (2021) · 피인용 35
p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation.

American journal of human genetics (2016) · 피인용 34
A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex.

eLife (2017) · 피인용 92
Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.

Molecular neurobiology (2020) · 피인용 31
Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats.

Cell reports (2022) · 피인용 31
Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells.

Developmental cell (2021) · 피인용 83
Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability.

Neural regeneration research (2022) · 피인용 56
Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer's disease.

Molecular neurobiology (2021) · 피인용 29
NGF-Induced Nav1.7 Upregulation Contributes to Chronic Post-surgical Pain by Activating SGK1-Dependent Nedd4-2 Phosphorylation.

Molecular cell (2019) · 피인용 259
Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix.

Cell reports (2020) · 피인용 101
Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis.

Cell reports (2020) · 피인용 44
The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis.

eLife (2017) · 피인용 647
Diverse stimuli engage different neutrophil extracellular trap pathways.

Cell metabolism (2019) · 피인용 139
Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models.

Proceedings of the National Academy of Sciences of the United States of America (2022) · 피인용 132
Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages.

Molecular cell (2017) · 피인용 382
Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

Current biology : CB (2020) · 피인용 80
Ghrelin Signaling Affects Feeding Behavior, Metabolism, and Memory through the Vagus Nerve.

Journal of neurochemistry (2024) · 피인용 30
Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline.

Cell (2021) · 피인용 523
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.

Immunity (2018) · 피인용 166
The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation.

Molecular cell (2020) · 피인용 90
Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs.

British journal of pharmacology (2022) · 피인용 77
Honokiol ameliorates cisplatin-induced acute kidney injury via inhibition of mitochondrial fission.

British journal of pharmacology (2023) · 피인용 28
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.

iScience (2023) · 피인용 14
Gasdermin D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway.

Cell reports (2022) · 피인용 59
K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy.

Journal of biomedical science (2019) · 피인용 54
Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways.

Cell reports (2022) · 피인용 42
Secreted NF-κB suppressive microbial metabolites modulate gut inflammation.

eLife (2019) · 피인용 49
Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts.

Cell reports (2020) · 피인용 9
The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) · 피인용 8
Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling.