Cell metabolism (2020) · 피인용 157
Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity.

Molecular cell (2021) · 피인용 90
TopBP1 assembles nuclear condensates to switch on ATR signaling.

eLife (2019) · 피인용 50
Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.

Cancer cell (2021) · 피인용 140
Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis.

Molecular cell (2022) · 피인용 65
Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS.

Cell reports (2021) · 피인용 42
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment.

Cancer cell (2020) · 피인용 113
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.

Cell reports. Medicine (2021) · 피인용 78
<i>CCNE1</i> copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models.

The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) · 피인용 59
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.

Molecular cell (2023) · 피인용 73
DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C.

Cell reports. Medicine (2024) · 피인용 44
Immunomodulatory effects and improved outcomes with cisplatin- versus carboplatin-based chemotherapy plus atezolizumab in urothelial cancer.

Molecular cancer therapeutics (2024) · 피인용 19
PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer.

Cell reports (2022) · 피인용 55
ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.

Molecular cell (2021) · 피인용 51
Reading ADP-ribosylation signaling using chemical biology and interaction proteomics.

Cell reports (2022) · 피인용 17
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.

Molecular cell (2022) · 피인용 45
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts.

Nature communications (2024) · 피인용 9
PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma.

Oncogene (2025) · 피인용 4
Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer.

Cell (2025) · 피인용 22
Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors.

Translational oncology (2023) · 피인용 8
The ATR inhibitor VE-821 increases the sensitivity of gastric cancer cells to cisplatin.

Cell reports (2026) · 피인용 0
Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer.

Cell reports (2019) · 피인용 53
Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2.

Immunity (2020) · 피인용 38
Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis.

eLife (2021) · 피인용 35
The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure.

Molecular cell (2021) · 피인용 90
TopBP1 assembles nuclear condensates to switch on ATR signaling.

Molecular cell (2024) · 피인용 39
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape.

STAR protocols (2021) · 피인용 17
An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells.

Cell (2025) · 피인용 22
Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors.

Cell reports (2023) · 피인용 18
Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response.

iScience (2025) · 피인용 1
Nucleolar stress facilitates islet β cell senescence via hijacking the DNA damage response pathways.

Molecular cell (2024) · 피인용 27
IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors.

Molecular carcinogenesis (2026) · 피인용 0
Protein Phosphatase 2 Is Required for Metastatic Dormancy and Is Regulated by Histone Demethylase KDM5A.

Cell reports. Medicine (2023) · 피인용 24
PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition.

Current biology : CB (2025) · 피인용 5
The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis.

ASN neuro (2023) · 피인용 5
Upregulated DNA Damage-Linked Biomarkers in Parkinson's Disease Model Mice.

eLife (2017) · 피인용 52
A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.

Translational lung cancer research (2023) · 피인용 1
KMT2C expression and DNA homologous recombination repair factors in lung cancers with a high-grade fetal adenocarcinoma component.

Current biology : CB (2020) · 피인용 56
The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis.

Cell reports (2020) · 피인용 14
L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2024) · 피인용 4
β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models.

Cell chemical biology (2020) · 피인용 65
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.