Cell reports (2019) · 피인용 80
PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis.

Cell reports (2020) · 피인용 70
Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection.

Molecular cell (2022) · 피인용 65
Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS.

Cell reports (2020) · 피인용 86
Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response.

Cell reports (2021) · 피인용 68
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.

eLife (2018) · 피인용 65
Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.

Molecular cell (2021) · 피인용 134
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Molecular cell (2019) · 피인용 58
RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

eLife (2020) · 피인용 54
ATR expands embryonic stem cell fate potential in response to replication stress.

Cell stem cell (2020) · 피인용 96
Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability.

Cell chemical biology (2020) · 피인용 65
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.

Cell reports (2020) · 피인용 27
TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.

EBioMedicine (2021) · 피인용 17
MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway.

Open biology (2024) · 피인용 7
A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells.

Cell reports (2026) · 피인용 0
Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer.

Molecular cell (2019) · 피인용 115
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.

Cell reports (2022) · 피인용 55
ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.

eLife (2019) · 피인용 50
Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.

Cancer research (2022) · 피인용 46
Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors.

Cell reports (2023) · 피인용 29
Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma.

Endocrinology (2018) · 피인용 9
ATM Is Required for the Prolactin-Induced HSP90-Mediated Increase in Cellular Viability and Clonogenic Growth After DNA Damage.

The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) · 피인용 59
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.

Cell metabolism (2021) · 피인용 45
Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair.

The Journal of biological chemistry (2021) · 피인용 18
Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double-strand break repair.

Cell reports (2022) · 피인용 20
The splicing regulators TIA1 and TIAL1 are required for the expression of the DNA damage repair machinery during B cell lymphopoiesis.

The Journal of biological chemistry (2021) · 피인용 18
Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double-strand break repair.

Science advances (2025) · 피인용 15
Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair.

Cell reports (2020) · 피인용 27
TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.

eLife (2023) · 피인용 23
Systematic analysis of the molecular and biophysical properties of key DNA damage response factors.

Cell metabolism (2020) · 피인용 157
Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity.

eLife (2021) · 피인용 17
The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice.

ASN neuro (2023) · 피인용 5
Upregulated DNA Damage-Linked Biomarkers in Parkinson's Disease Model Mice.

NPJ precision oncology (2026) · 피인용 0
DDX41 facilitates PD-L1-mediated immune escape in OSCC via the phase separation and activation STING pathway.

iScience (2021) · 피인용 35
ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability.

Cell reports (2019) · 피인용 16
Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-α-Induced Apoptosis via Different Routes.

Molecular cell (2020) · 피인용 38
DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1.

Cancer cell (2021) · 피인용 140
Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis.

Cell reports (2019) · 피인용 45
DNA Damage Activates TGF-β Signaling via ATM-c-Cbl-Mediated Stabilization of the Type II Receptor TβRII.

Cell reports (2019) · 피인용 67
PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.

ASN neuro (2023) · 피인용 5
Upregulated DNA Damage-Linked Biomarkers in Parkinson's Disease Model Mice.

Cell reports (2023) · 피인용 5
ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen.

Cell reports (2020) · 피인용 14
L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis.

Molecular cell (2021) · 피인용 68
The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability.